Beating the Odds in Uganda

Protein engineering: Beating the odds.

Millions of novel protein sequences are currently being discovered, at an incredible pace. For instance, a recent article1 described the identifi cation of 8 complete and 789 draft genomes within a single metagenome library from an aquifer water sample. Unfortunately, the analysis of this huge pool of sequences remains challenging, given that the function of ~30–40% of the genes remains unknown...

Beating the Odds in Teaching All Children to Read

Beating the Odds: Intact Neuropsychological Functioning despite TLE

Patients with Temporal lobe epilepsy (TLE) frequently display cognitive comorbidity and can have widespread network abnormalities, which might affect a variety of cognitive and intellectual functions. As a result, refractory TLE seems to be associated with slow but ongoing cognitive deterioration. The case is of a 32 year old, right handed male, engineering graduate, diagnosed with TLE- right m...

Beating the odds: a cardiomyocyte cell line at last.

ways and nuclear transcription factors that regulate cardiac myocyte differentiation is a problem that has both fascinated and vexed developmental biologists and cardiologists for more than 20 years. The answer to this puzzle would provide important new information about how disparate signaling pathways evolved to regulate the differentiation of closely related, but distinct, mesodermal cell li...

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